Promega UK Blog
Spotlight: A Conversation with Dr Mhairi Morris Exploring How Exercise Shapes Cancer Biology in 3D
At Loughborough University, researchers are investigating how exercise shapes cancer biology within the tumour microenvironment. We spoke with Dr Mhairi Morris to learn how her team uses the CellTiter-Glo® 3D Cell Viability Assay to explore the links between breast cancer, obesity and the impact of physical activity in their advanced 3D cell culture model.
Grant Harradence from Abzena discusses how the use of CellTiter-Glo® Cell Viability Assay for early Antibody Drug Conjugate (ADC) candidate selection and RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay for advanced insights into bioconjugates’ mode of action, enhances both the data quality and efficiency of the ADC discovery process.
At the 2024 World Organoid Research Day Conference, Dr. Darren Heywood highlighted Promega’s 3D cell-based assays, focusing on endpoint, media sampling and real-time techniques to monitor cell health in 3D cell culture models.
Dr David Hay and Alvile Kasarinaite describe their use of Triglyceride-Glo™ Assay for measuring lipid levels in lab grown 3D liver cultures.
Dr Marta Ciechońska, Dr Rob Bradley and Dr Matthew Carey at Salient Bio describe how they are using Promega’s Maxwell HT® extraction chemistry with Analytik Jena’s CyBio® FeliX Liquid Handler to automate nucleic acid purification from microbiome samples.
Dr Ruth Carmichael from the University of Exeter describes her endogenous tagging strategy for measuring protein expression, using Nano-Glo® Dual-Luciferase® Reporter technology and the GloMax® Discover.
Professor Alain Kohl, Professor in Virology at Liverpool School of Tropical Medicine and Dr Akira Alexander describe how the small size of the bioluminescent peptide tag, HiBiT, makes it an ideal reporter for virology research.
Dr. Stuart McElroy describes how his team at BioAscent used the NAD(P)H-Glo™ Assay to screen 50,000 compounds against a potential drug target.
Samantha Llewellyn, Swansea University, discusses her work on predictive 3D liver models for nanomaterial safety assessment.
Dr Jacek Mokrosinski, discusses how the small size and brightness of NanoBiT® has enabled him to study β-arrestin recruitment to GPCRs in real time, in live cells.
ROS-Glo™ H2O2 Assay in an assay cascade to discover new drugs for diseases related to mitochondrial disfunction.
Prof. Ben Housden from the University of Exeter describes his work on
high-throughput genetic screens and how he utilises CellTiter-Glo® reagent to monitor cell viability.
Dr Tracey Martin from Cardiff University describes the advantages of using the Lumit™ Cellular Systems Kit when screening novel compounds for drug discovery.
Dr. Stuart McElroy describes how his team at BioAscent used the NAD(P)H-Glo™ Assay to screen 50,000 compounds against a potential drug target.
Dr Joanna Greenhough discusses Promega’s products that support the NGS workflow, including long-read sequencing.
Dr Seydou Yao, Swansea University, discusses development of novel therapeutics to target endometrial and ovarian tumours.
Paul Horrocks, Professor of Molecular Parasitology at Keele University, discusses his research focused on the biology of the human malarial parasite P. falciparum and understanding the dynamics of drug action.
Rennos Fragkoudis from the Edinburgh Genome Foundry explains how their DNA engineering workflows benefit from automating nucleic acid extraction using Promega’s Wizard® SV96 Plasmid Purification Kit with TECAN’s Liquid Handler.
Dr Rob Bradley and
Dr Matthew Carey at Salient Bio describe how they are using Promega’s Maxwell HT® extraction chemistry with Analytik Jena’s CyBio® FeliX Liquid Handler to automate nucleic acid purification from microbiome samples.
Great Ormond Street Hospital – The use ProNex® chemistry to support Next-Generation Sequencing.
Oxford Genetics' unique high-throughput platform has been developed using Promega chemistry for antibody engineering in synthetic biology.
Dr Suet-Feung Chin at the Cancer Research UK Cambridge Institute describes how they automated nucleic acid purification.
HLA Typing at Anthony Nolan Research Institute: Promega’s Products Supporting a Long-read Next Generation Sequencing Workflow.
Dr Marta Ciechońska,
Dr Rob Bradley and
Dr Matthew Carey at
Salient Bio describe how they are using Promega’s Maxwell HT® extraction chemistry with Analytik Jena’s
CyBio® FeliX Liquid Handler to automate nucleic acid purification from
microbiome samples.
Primerdesign UK Ltd Promega’s Custom Manufacturing Services Supporting Real-Time PCR Assay Production, Including a Recently Developed SARS-CoV-2 Diagnostic Kit.
Natalie Jorgensen from Manchester University discusses the implementation and provision of an MSI diagnostic service, at the North West Genomic Laboratory Hub, Manchester, UK.
