How the Compact Design of the MyGlo^® Reagent Reader Enables Real-Time Pathogen Tracking in High-Containment Laboratories

Professor Rachel Simmonds, Professor of Immunopathogenesis at the University of Surrey, investigates Buruli ulcer, a neglected tropical disease caused by Mycobacterium ulcerans. In this video case study, she explains how her team uses luminescent reporter strains and the MyGlo® Reagent Reader to track bacterial growth inside macrophages within a high-containment laboratory.

The MyGlo's compact footprint allows it to operate inside a biosafety cabinet, enabling real-time luminescence measurements on live hazardous organisms entirely within containment. Professor Simmonds discusses how this capability has unlocked growth assays that were previously very challenging with traditional methods. This approach has enabled the team to generate new insights into host–pathogen interactions of Buruli ulcer.

Learn more about the MyGlo luminometer >