Reporter Vectors and Cell Lines

NanoLuc® Luciferase Reporters

State-of-the-art reporter technology offering unrivaled sensitivity and versatility in a very small luciferase. Find the pNL reporter that is right for your application.

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pmirGLO Dual-Luciferase miRNA Target Expression Vector

Quantitatively measure microRNA activity with a luciferase reporter. The firefly luciferase (luc2) vector is the primary reporter to monitor mRNA regulation and Renilla luciferase (hRluc-neo) acts as a control reporter for normalization and selection.

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pGL4 Luciferase Reporter Vectors

These next generation, luciferase reporter vectors offer more efficient expression of both firefly and Renilla luciferases in mammalian cells. 

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GloResponse™ Luciferase Reporter Cell Lines

Experience state-of-the-art luciferase reporter technology integrated into a cell line. Develop a reporter assay based on the pathway of interest regulating the luciferase gene.

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This chapter of the Protocols and Applications Guide discusses the use of bioluminescent reporters to study eukarytoic gene expression and regulation including the use of single-reporter assays, dual-reporter assays, and live-cell substrates.

This animation introduces the concept of reporter gene assays, using the Dual-Luciferase® Assay as a model.