Promega Corporation

ALK2 Kinase Enzyme System

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Recombinant human ALK2 (147–end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8. Knockdown of ALK2, but not TGFβRI (ALK5), abrogates endoglin-mediated decrease in cell motility of prostate cancer cells, and constitutively active ALK2 is sufficient to restore a low-motility phenotype in endoglin-deficient cells (1). Therefore, endoglin decreases prostate cancer cell motility through activ...

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Product Size Conc. Catalog # *List Price Order QTY Add to Cart
ALK2 Kinase Enzyme System
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ALK2 Kinase Enzyme System  Components

10μg
- V4492 £ 251.00 Add to cart

ALK2 Kinase Enzyme System

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ALK2 Kinase Enzyme System

 Components

1mg
- V6272 Please Enquire
ADP-Glo™ Kinase Assay + ALK2 Kinase Enzyme System
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ADP-Glo™ Kinase Assay + ALK2 Kinase Enzyme System  Components

  • ALK2 Kinase Enzyme System

    V44921 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4493 £ 479.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V4492, V6272, V4493 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V4493 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V4493 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V4493 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V4493 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V4493 U.S. Pat. No. 8,183,007 and other patents pending.

V4493 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V4493 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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